Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | TDO2 | P48775 | 2/20 | 0.47 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PTGFR | P43088 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718964 | 0.84 | KMT2A (0.47) | KMT2AIDO1TDO2IDO2PTGDR2 | |
| SCHEMBL22945646 | 0.83 | KMT2A (0.46) | KMT2APTGDR2ALOX15ACP3CASP1 | |
| SCHEMBL24488931 | 0.83 | KMT2A (0.46) | KMT2APTGDR2ALOX15ACP3CASP1 | |
| SCHEMBL29694301 | 0.83 | KMT2A (0.46) | KMT2APTGDR2ALOX15ACP3CASP1 | |
| Hydrochloric Acid SCHEMBL21631999 | 0.79 | KMT2A (0.42) | KMT2AIDO1TDO2IDO2PTGDR2 | |
| SCHEMBL10334624 | 0.79 | ESR1 (0.52) | KMT2AALOX15ACP3GLAL3MBTL1 | |
| SCHEMBL10334935 | 0.77 | IDO1 (0.58) | IDO1TDO2PTGDR2 | |
| SCHEMBL167430 | 0.75 | ALOX15 (0.48) | ALOX15 | |
| SCHEMBL9292723 | 0.75 | PTGDR2 (0.49) | KMT2AIDO1TDO2PTGDR2L3MBTL1 | |
| SCHEMBL8015435 | 0.75 | IDO1 (0.38) | KMT2AIDO1TDO2IDO2CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4205087-A | ANTIARTHRITIC AGENTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-05-27 | — | — | US | claimed |
| US-4205087-A | ANTIARTHRITIC AGENTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-05-27 | — | — | US | disclosed |