Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11437752 | 0.84 | KMT2A (0.49) | KMT2AAKR1B1PTGDR2CXCL8ACP3 | |
| SCHEMBL29694301 | 0.81 | KMT2A (0.46) | KMT2APTGDR2CXCL8ACP3CASP1 | |
| SCHEMBL24488931 | 0.81 | KMT2A (0.46) | KMT2APTGDR2CXCL8ACP3CASP1 | |
| SCHEMBL22945646 | 0.81 | KMT2A (0.46) | KMT2APTGDR2CXCL8ACP3CASP1 | |
| SCHEMBL28444913 | 0.78 | ALOX15 (0.45) | KMT2AAKR1B1ALOX15GLAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL21631999 | 0.78 | KMT2A (0.42) | KMT2APTGDR2ACP3CASP1ALOX15 | |
| SCHEMBL2345812 | 0.77 | ACP3 (0.43) | KMT2AAKR1B1CXCL8ACP3CASP1 | |
| SCHEMBL4607561 | 0.74 | ACP3 (0.41) | KMT2AAKR1B1CXCL8ACP3CASP1 | |
| SCHEMBL23293691 | 0.73 | LPAR1 (0.39) | KMT2AAKR1B1CXCL8CASP1MEN1 | |
| SCHEMBL11047144 | 0.73 | AKR1B1 (0.47) | KMT2AAKR1B1ACP3CASP1CACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482571-A | BENZYLOXY ACIDS | UNIVERSITY OF PITTSBURGH (US) | 1984-11-13 | — | — | US | claimed |
| EP-0240256-B1 | COMPOUNDS USEFUL IN TREATING SICKLE CELL ANEMIA | MERCK & CO. INC. (US) | 1992-04-29 | — | — | EP | disclosed |
| US-4731473-A | Compounds useful in treating sickle cell anemia | MERCK & CO., INC. (US) | 1988-03-15 | — | — | US | disclosed |
| EP-0240256-A2 | Compounds useful in treating sickle cell anemia | MERCK & CO. INC. (US) | 1987-10-07 | — | — | EP | disclosed |
| US-4482571-A | BENZYLOXY ACIDS | UNIVERSITY OF PITTSBURGH (US) | 1984-11-13 | — | — | US | disclosed |
| US-4482571-A | BENZYLOXY ACIDS | UNIVERSITY OF PITTSBURGH (US) | 1984-11-13 | — | — | US | disclosed |