Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.39 |
| ▸ | PTGFR | P43088 | 2/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24488931 | 1.00 | KMT2A (0.46) | KMT2ACASP1NPC1ADRB2ADRB1 | |
| SCHEMBL29694301 | 1.00 | KMT2A (0.46) | KMT2ACASP1NPC1ADRB2ADRB1 | |
| SCHEMBL24488935 | 0.84 | LMNA (0.44) | KMT2ACASP1NPC1ADRB2ADRB1 | |
| SCHEMBL11437752 | 0.83 | KMT2A (0.49) | KMT2ACASP1GLAL3MBTL1PTGDR2 | |
| SCHEMBL15551258 | 0.81 | CASP1 (0.51) | KMT2ACASP1NPC1MEN1POLB | |
| SCHEMBL9718964 | 0.81 | KMT2A (0.47) | KMT2ACASP1GLAL3MBTL1PTGDR2 | |
| SCHEMBL8308822 | 0.80 | HIF1A (0.44) | KMT2AGLAL3MBTL1MEN1POLB | |
| SCHEMBL8906867 | 0.77 | LPAR1 (0.49) | CASP1ADRB2ADRB1LPAR1ALDH1A1 | |
| SCHEMBL22824154 | 0.77 | CASP1 (0.44) | CASP1ADRB2ADRB1GLAL3MBTL1 | |
| SCHEMBL16672851 | 0.77 | FFAR1 (0.49) | KMT2AGLAL3MBTL1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021020429-A1 | UREA COMPOUND FOR ANTAGONIZING LPA1 RECEPTOR | 大正製薬株式会社 | 2021-02-04 | — | — | WO | disclosed |