Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11448317 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL11437542 | 0.80 | MEN1 (0.46) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL11446742 | 0.79 | MEN1 (0.45) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL11437571 | 0.78 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL11338362 | 0.78 | KDM4E (0.47) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL11434873 | 0.77 | CHRM2 (0.42) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL11454746 | 0.76 | SIGMAR1 (0.51) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL11331578 | 0.75 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL11546924 | 0.75 | MEN1 (0.47) | ALDH1A1MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL11446905 | 0.73 | MEN1 (0.38) | ALDH1A1MEN1KMT2AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217362-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| US-4212888-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4128663-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |