Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 16/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11339650 | 0.96 | SIGMAR1 (0.53) | SIGMAR1OPRK1KDM4EMEN1NPC1 | |
| SCHEMBL11341260 | 0.91 | SIGMAR1 (0.43) | SIGMAR1OPRK1KDM4EMEN1NPC1 | |
| SCHEMBL11446429 | 0.90 | SIGMAR1 (0.51) | SIGMAR1OPRK1KDM4EMEN1NPC1 | |
| SCHEMBL11447938 | 0.89 | SIGMAR1 (0.53) | SIGMAR1OPRK1 | |
| SCHEMBL11343008 | 0.86 | SIGMAR1 (0.53) | SIGMAR1OPRK1KDM4EMEN1NPC1 | |
| SCHEMBL11341263 | 0.85 | SIGMAR1 (0.55) | SIGMAR1OPRK1MEN1ALDH1A1RAB9A | |
| SCHEMBL11447936 | 0.84 | SIGMAR1 (0.41) | SIGMAR1OPRK1KDM4EMEN1NPC1 | |
| SCHEMBL11336355 | 0.83 | SIGMAR1 (0.50) | SIGMAR1OPRK1KDM4EMEN1NPC1 | |
| SCHEMBL11336349 | 0.83 | SIGMAR1 (0.50) | SIGMAR1OPRK1KDM4EMEN1NPC1 | |
| SCHEMBL11338316 | 0.82 | SIGMAR1 (0.44) | SIGMAR1OPRK1KDM4EMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204003-A | N-(2-Aminocyclopentyl)-N-alkanoylanilides as CNS anti-depressants | THE UPJOHN COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
| US-4159340-A | N-(2-Aminocyclopentyl)-N-acylanilides as CNS anti-depressants | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4157398-A | N-(2-Aminocyclopentyl)acylanilides and treating depression | THE UPJOHN COMPANY (US) | 1979-06-05 | — | — | US | disclosed |
| US-4156733-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-05-29 | — | — | US | disclosed |
| US-4156015-A | N-(2-Aminocyclopentyl)acylanilides and treating depression | THE UPJOHN COMPANY (US) | 1979-05-22 | — | — | US | disclosed |
| US-4148913-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-04-10 | — | — | US | disclosed |