Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.39 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.39 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | CBX7 | O95931 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11440789 | 0.91 | CASP6 (0.43) | CASP6CTDSP1CYP1A2AURKAAURKB | |
| SCHEMBL11428137 | 0.87 | CASP6 (0.47) | CASP6CTDSP1CYP1A2ENPP2MAPT | |
| SCHEMBL11345207 | 0.86 | HPSE (0.50) | CYP1A2MAPTMEN1KMT2AHPSE | |
| SCHEMBL10907541 | 0.86 | HPSE (0.46) | CASP6CTDSP1CYP1A2ENPP2MAPT | |
| SCHEMBL11430988 | 0.85 | CASP6 (0.59) | CASP6CTDSP1ENPP2TTRMAPT | |
| SCHEMBL11425978 | 0.84 | ULK1 (0.50) | CASP6CTDSP1TTRSTAT3MEN1 | |
| SCHEMBL11425190 | 0.83 | MEN1 (0.56) | MAPTTP53MEN1KMT2ATDP1 | |
| SCHEMBL11439440 | 0.83 | TTR (0.43) | CASP6CTDSP1CYP1A2AURKAAURKB | |
| SCHEMBL11438775 | 0.83 | PLG (0.42) | CYP1A2AURKAAURKBTTRTP53 | |
| SCHEMBL11438820 | 0.82 | CASP6 (0.40) | CASP6CTDSP1AURKAAURKBENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |