Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | PI4KA | P42356 | 2/20 | 0.56 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.56 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | XDH | P47989 | 1/20 | 0.56 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.56 |
| ▸ | PNP | P00491 | 1/20 | 0.46 |
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenine SCHEMBL8469554 | 0.86 | ALDH1A1 (0.43) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| Adenine SCHEMBL8820867 | 0.83 | PI4KA (0.81) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| Hypoxanthine SCHEMBL11439069 | 0.83 | ALDH1A1 (0.56) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| Adenine SCHEMBL8110 | 0.82 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL3413247 | 0.82 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL3416954 | 0.82 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL3414603 | 0.82 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL8607558 | 0.81 | ALDH1A1 (0.45) | ALDH1A1PI4KAPI4K2BPI4K2API4KB | |
| Adenine SCHEMBL11798390 | 0.80 | PI4KA (0.50) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL4595803 | 0.80 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993017035-A1 | 2'ISODIDEOXY-β-D-NUCLEOSIDES AS STABLE ANTIVIRAL AGENTS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1993-09-02 | — | — | WO | claimed |
| EP-3833761-A1 | NOVEL CAS12B ENZYMES AND SYSTEMS | The Broad Institute, Inc. (US) | 2021-06-16 | — | — | EP | disclosed |
| EP-3830256-A2 | NOVEL CRISPR ENZYMES AND SYSTEMS | The Broad Institute, Inc. (US) | 2021-06-09 | — | — | EP | disclosed |
| EP-3728576-A1 | CAS12B SYSTEMS, METHODS, AND COMPOSITIONS FOR TARGETED RNA BASE EDITING | The Broad Institute, Inc. (US) | 2020-10-28 | — | — | EP | disclosed |
| WO-2020033601-A1 | NOVEL CAS12B ENZYMES AND SYSTEMS | THE BROAD INSTITUTE, INC. (US) | 2020-02-13 | — | — | WO | disclosed |
| WO-2020028555-A2 | NOVEL CRISPR ENZYMES AND SYSTEMS | THE BROAD INSTITUTE, INC. (US) | 2020-02-06 | — | — | WO | disclosed |
| WO-2018183908-A1 | COMPOSITIONS AND METHODS FOR TREATING OVARIAN TUMORS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-10-04 | — | — | WO | disclosed |
| WO-1997043641-A1 | MOLECULAR DIVERSITY SCREENING DEVICE AND METHOD | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1997-11-20 | — | — | WO | disclosed |
| US-5686253-A | Method of stabilizing enzyme conjugates | BEHRINGWERKE AG (DE) | 1997-11-11 | — | — | US | disclosed |
| US-5273885-A | Using a polyiodothyronine analog of a phenyl compound containing a hydroxyl group ortho to an iodine | SYNTEX (U.S.A.) INC. (US) | 1993-12-28 | — | — | US | disclosed |
| US-4376825-A | ENZYME-BOUND LIGANDS WITH FREE REACTIVE SITES WHICH CAN BIND RECEPTORS | SYVA COMPANY (US) | 1983-03-15 | — | — | US | disclosed |
| US-4282325-A | FOR AMPLIFICATION IN ASSAYS | SYVA COMPANY (US) | 1981-08-04 | — | — | US | disclosed |
| US-4203802-A | ENZYME BOUND TO AN ESTROGEN LIGAND | SYVA COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
| US-4190496-A | RECEPTOR, LIGAND, AND ENZYME-BOUND | SYVA COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4067774-A | Compounds for enzyme amplification assay | SYVA COMPANY (US) | 1978-01-10 | — | — | US | disclosed |
| US-3975237-A | LIGANDS | SYVA COMPANY (US) | 1976-08-17 | — | — | US | disclosed |
| US-3966556-A | Compounds for enzyme amplification assay methadone analogs | SYVA COMPANY (US) | 1976-06-29 | — | — | US | disclosed |