Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.50 |
| ▸ | CASP6 | P55212 | 5/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 3/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11433775 | 0.92 | CASP6 (0.55) | NT5ECASP6CYP2C9ALDH1A1HSD17B10 | |
| SCHEMBL11428936 | 0.91 | NT5E (0.50) | NT5ECASP6CYP2C9ALDH1A1HSD17B10 | |
| SCHEMBL11204762 | 0.91 | NT5E (0.62) | NT5ECASP6CYP2C9ALDH1A1HSD17B10 | |
| SCHEMBL11439176 | 0.86 | NT5E (0.45) | NT5ECASP6CYP2C9ALDH1A1CTDSP1 | |
| SCHEMBL11440916 | 0.86 | CASP6 (0.64) | NT5ECASP6CTDSP1SNCANSD2 | |
| SCHEMBL11439237 | 0.85 | CYP2C9 (0.47) | NT5ECASP6CYP2C9ALDH1A1HSD17B10 | |
| SCHEMBL11437160 | 0.84 | KCNMA1 (0.45) | NT5ECASP6CYP2C9ALDH1A1CTDSP1 | |
| SCHEMBL11428916 | 0.83 | CASP6 (0.55) | NT5ECASP6CYP2C9ALDH1A1HSD17B10 | |
| SCHEMBL11425646 | 0.83 | ALDH1A1 (0.42) | NT5ECASP6CYP2C9ALDH1A1HSD17B10 | |
| SCHEMBL11438830 | 0.83 | CYP2C9 (0.44) | NT5ECASP6CYP2C9ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |