Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.32 |
| ▸ | CCKAR | P32238 | 2/20 | 0.31 |
| ▸ | CCKBR | P32239 | 2/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | WEE1 | P30291 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11434332 | 0.84 | BRD4 (0.40) | BRD4CCKARCCKBRFAAHMGLL | |
| SCHEMBL11557184 | 0.83 | — | — | |
| SCHEMBL11428536 | 0.80 | BRD9 (0.41) | — | |
| SCHEMBL11434573 | 0.76 | BRD4 (0.40) | BRD4 | |
| SCHEMBL11440224 | 0.72 | HSD17B10 (0.41) | BRD4 | |
| SCHEMBL11434388 | 0.71 | MAOB (0.44) | — | |
| SCHEMBL11550813 | 0.70 | BRD4 (0.41) | BRD4MGLL | |
| SCHEMBL11428401 | 0.69 | AKR1C3 (0.42) | CCKBR | |
| SCHEMBL11431671 | 0.69 | EGFR (0.50) | — | |
| SCHEMBL11441378 | 0.69 | BRD4 (0.43) | BRD4FAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |