Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 4/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAT2A | P31153 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11434573 | 0.95 | BRD4 (0.40) | BRD4MAOB | |
| SCHEMBL11426220 | 0.89 | BRD4 (0.44) | HSD17B10BRD4HPGDLMNA | |
| SCHEMBL11435913 | 0.86 | EGFR (0.44) | BRD4HPGDKDM4E | |
| SCHEMBL11554969 | 0.85 | BRD4 (0.43) | BRD4LMNA | |
| SCHEMBL11441378 | 0.85 | BRD4 (0.43) | HSD17B10BRD4HTTKDM4ENPSR1 | |
| SCHEMBL11441314 | 0.84 | BRD4 (0.52) | HSD17B10BRD4HTTKDM4ESMN1; SMN2 | |
| SCHEMBL23147236 | 0.84 | GPR35 (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL11435975 | 0.84 | BRD9 (0.42) | MAOBMAT2A | |
| SCHEMBL11434891 | 0.83 | KDM4E (0.35) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL11434522 | 0.82 | CNR2 (0.43) | BRD4MAOBHPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | claimed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | claimed |
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |