Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 11/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | CCKAR | P32238 | 2/20 | 0.34 |
| ▸ | CCKBR | P32239 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441378 | 0.85 | BRD4 (0.43) | BRD4HSD17B10CREBBPFAAHMGLL | |
| SCHEMBL11441314 | 0.84 | BRD4 (0.52) | BRD4HSD17B10CREBBPMGLL | |
| SCHEMBL11439399 | 0.84 | BRD4 (0.32) | BRD4FAAHMGLLCCKARCCKBR | |
| SCHEMBL11428536 | 0.83 | BRD9 (0.41) | HSD17B10 | |
| SCHEMBL11434522 | 0.82 | CNR2 (0.43) | BRD4CREBBP | |
| SCHEMBL11429310 | 0.81 | MAOA (0.40) | BRD4HSD17B10CREBBP | |
| SCHEMBL11547644 | 0.81 | BRD4 (0.48) | BRD4HSD17B10CREBBPFAAHMGLL | |
| SCHEMBL11440224 | 0.81 | HSD17B10 (0.41) | BRD4HSD17B10 | |
| SCHEMBL11178194 | 0.81 | BRD4 (0.40) | BRD4HSD17B10 | |
| SCHEMBL11426574 | 0.81 | BAZ2B (0.44) | BRD4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4219507-A | SELECTIVE HYDROGENATION | MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) | 1980-08-26 | — | — | US | disclosed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |