Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.73 |
| ▸ | HPGD | P15428 | 5/20 | 0.73 |
| ▸ | HTT | P42858 | 4/20 | 0.69 |
| ▸ | RAD52 | P43351 | 1/20 | 0.68 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | GFER | P55789 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RPS6KA5 | O75582 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17199042 | 0.91 | KDM4E (0.62) | KDM4EALDH1A1HPGDHTTRAD52 | |
| SCHEMBL2882835 | 0.90 | KDM4E (0.62) | KDM4EALDH1A1HPGDHTTRAD52 | |
| SCHEMBL11443284 | 0.88 | KDM4E (0.74) | KDM4EALDH1A1HPGDHTTRAD52 | |
| SCHEMBL11442111 | 0.85 | KDM4E (0.71) | KDM4EALDH1A1HPGDHTTRAD52 | |
| SCHEMBL21777019 | 0.84 | KDM4E (1.00) | KDM4EALDH1A1HPGDHTTNLRP3 | |
| SCHEMBL1378639 | 0.82 | CYP11B2 (0.62) | KDM4EALDH1A1HPGDHTTRAD52 | |
| SCHEMBL616998 | 0.82 | KDM4E (0.97) | KDM4EALDH1A1HPGDHTTRAD52 | |
| Hydrochloric Acid SCHEMBL6605580 | 0.81 | KDM4E (1.00) | KDM4EALDH1A1HPGDHTTRAD52 | |
| Hydrochloric Acid SCHEMBL16736724 | 0.81 | KDM4E (1.00) | KDM4EALDH1A1HPGDHTTRAD52 | |
| SCHEMBL11449498 | 0.80 | KDM4E (0.63) | KDM4EALDH1A1HPGDHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4225492-A | Water-soluble disazo dyestuffs, prepared from unsymmetrical heterocyclic diamines | CASSELLA AKTIENGESELLSCHAFT (DE) | 1980-09-30 | — | — | US | disclosed |
| US-4144231-A | Soluble trisazo dyestuffs containing a 2-phenyl-benzimidazolyl, -benzoxazolyl or -benzthiazolyl middle component | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-03-13 | — | — | US | disclosed |
| US-4144230-A | Soluble trisazo dyestuffs containing a 2-phenyl-benzimidazolyl, -benzoxazolyl or -benzthiazolyl middle component | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-03-13 | — | — | US | disclosed |
| US-4143033-A | WATER-SOLUBLE DISAZO DYESTUFFS CONTAINING A 2-PHENYL-BENZIMIDAZOLYL,-BENZOXAZOLYL OR-BENZTHIAZOLYL MIDDLE COMPONENT | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-03-06 | — | — | US | disclosed |
| US-4137228-A | HIGH TINCTORIAL STRENGTH, COLORFASTNESS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-01-30 | — | — | US | disclosed |
| US-4033945-A | Water-soluble trisazo 8-amino-naphthol-1 dyes | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1977-07-05 | — | — | US | disclosed |