Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 7/20 | 0.44 |
| ▸ | MET | P08581 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11440224 | 0.89 | HSD17B10 (0.41) | BRD4HSD17B10LMNAHPGD | |
| SCHEMBL11554969 | 0.86 | BRD4 (0.43) | BRD4METLMNAMAPT | |
| SCHEMBL11441314 | 0.86 | BRD4 (0.52) | BRD4METHSD17B10CREBBPLMNA | |
| SCHEMBL11434573 | 0.83 | BRD4 (0.40) | BRD4MAPTUSP2ALDH1A1CYP1A2 | |
| SCHEMBL11556518 | 0.83 | MET (0.41) | BRD4METHSD17B10MAPTUSP2 | |
| SCHEMBL11547644 | 0.82 | BRD4 (0.48) | BRD4HSD17B10CREBBPLMNAMAPT | |
| SCHEMBL11426297 | 0.81 | BRD9 (0.53) | BRD4HSD17B10CREBBPMAPTALDH1A1 | |
| SCHEMBL11428389 | 0.80 | PTPRC (0.41) | BRD4HSD17B10CREBBPLMNAMAPT | |
| SCHEMBL11550813 | 0.80 | BRD4 (0.41) | BRD4HSD17B10LMNAMAPTALDH1A1 | |
| SCHEMBL11441378 | 0.79 | BRD4 (0.43) | BRD4HSD17B10CREBBPLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |