SCHEMBL11440342

SCHEMBL11440342

Cc1cc(NC(=O)C2(C)CC2)ccc1OC(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.42
CNR2 P34972 1/20 0.42
NPSR1 Q6W5P4 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
TRPV1 Q8NER1 2/20 0.39
BRAF P15056 1/20 0.39
KDR P35968 1/20 0.39
BACE1 P56817 1/20 0.38
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
THRB P10828 1/20 0.37
NPY2R P49146 1/20 0.36
PARP1 P09874 1/20 0.36
NR2E3 Q9Y5X4 1/20 0.36
LIMK2 P53671 1/20 0.36
CYP26A1 O43174 1/20 0.36
CYP26B1 Q9NR63 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11565436 0.85 HDAC1 (0.39) CNR1CNR2NPSR1MEN1KMT2A
SCHEMBL11567218 0.82 CNR1 (0.41) CNR1CNR2NPSR1MEN1KMT2A
SCHEMBL11435252 0.81 RORC (0.47) CNR1CNR2MAPTALDH1A1
SCHEMBL11045834 0.80 KMT2A (0.46) CNR1CNR2NPSR1MEN1KMT2A
SCHEMBL11435806 0.77 PDE4B (0.41) CNR1CNR2LMNA
SCHEMBL11562238 0.77 KDM4E (0.39) CNR1CNR2KMT2ABACE1ALDH1A1
SCHEMBL11440778 0.77 HDAC1 (0.42) CNR1CNR2
SCHEMBL11565472 0.77 CNR1 (0.43) CNR1CNR2NPSR1MEN1KMT2A
SCHEMBL11050975 0.76 PNLIP (0.49) MEN1KMT2ATRPV1BRAFKDR
SCHEMBL15886280 0.76 BACE1 (0.52) CNR1CNR2NPSR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4199347-A Cycloalkanecarboxanilide derivative herbicides SHELL OIL COMPANY (US) 1980-04-22 US disclosed
US-4166735-A Cycloalkanecarboxanilide derivative herbicides SHELL OIL COMPANY (US) 1979-09-04 US disclosed