Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 13/20 | 0.46 |
| ▸ | MEN1 | O00255 | 12/20 | 0.46 |
| ▸ | MAPT | P10636 | 12/20 | 0.46 |
| ▸ | LMNA | P02545 | 7/20 | 0.46 |
| ▸ | HTT | P42858 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | HTR1E | P28566 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11435252 | 0.88 | RORC (0.47) | MAPTALDH1A1SMN1; SMN2MAPK1RAB9A | |
| SCHEMBL11049200 | 0.87 | MEN1 (0.44) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL11050893 | 0.86 | SMN1; SMN2 (0.42) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL11054922 | 0.86 | MAPT (0.57) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL11050028 | 0.84 | BRAF (0.46) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL11562238 | 0.84 | KDM4E (0.39) | KMT2AALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11440778 | 0.84 | HDAC1 (0.42) | TSHRCNR1CNR2 | |
| SCHEMBL11567218 | 0.81 | CNR1 (0.41) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL11440342 | 0.80 | CNR1 (0.42) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL15886280 | 0.77 | BACE1 (0.52) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0052473-B1 | N-SUBSTITUTED PHENYL-1-METHYLCYCLOPROPANECARBOXAMIDES, THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-08-22 | — | — | EP | disclosed |
| US-4447260-A | N-Substituted phenyl-1-methylcyclopropanecarboxamides, and their herbicidal use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-05-08 | — | — | US | disclosed |
| EP-0052473-A2 | N-Substituted phenyl-1-methylcyclopropanecarboxamides, their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-05-26 | — | — | EP | disclosed |