Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11149112 | 0.78 | HSD11B1 (0.47) | HSD11B1ALDH1A1EPHX2L3MBTL1HSD17B10 | |
| Hydrochloric Acid SCHEMBL11154979 | 0.76 | HSD11B1 (0.45) | HSD11B1ALDH1A1EPHX2L3MBTL1HSD17B10 | |
| SCHEMBL11076676 | 0.75 | HSD11B1 (0.54) | HSD11B1P2RX7EPHX2L3MBTL1CXCR3 | |
| SCHEMBL158815 | 0.75 | HSD11B1 (0.54) | HSD11B1DPP4FAPDPP7EPHX2 | |
| Hydrochloric Acid SCHEMBL27500985 | 0.73 | HSD11B1 (0.52) | HSD11B1DPP4FAPDPP7EPHX2 | |
| SCHEMBL11156387 | 0.72 | HSD11B1 (0.40) | HSD11B1ALDH1A1EPHX2L3MBTL1CXCR3 | |
| SCHEMBL1787432 | 0.72 | HSD11B1 (1.00) | HSD11B1P2RX7EPHX2L3MBTL1HSD17B10 | |
| Hydrochloric Acid SCHEMBL11152826 | 0.71 | HSD11B1 (0.39) | HSD11B1ALDH1A1EPHX2L3MBTL1CXCR3 | |
| SCHEMBL11442309 | 0.71 | HSD11B1 (0.41) | HSD11B1P2RX7EPHX2L3MBTL1 | |
| SCHEMBL11442077 | 0.70 | CXCR3 (0.38) | HSD11B1L3MBTL1CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202892-A | FUNGICIDES, VIRICIDES, ANTIPROTOZOA AGENTS, PARKINSON'S DISEASE | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1980-05-13 | — | — | US | claimed |
| EP-0002065-A1 | Methyladamantyl hydrazines, their pharmaceutically acceptable salts and pharmaceutical compositions containing them | Teva Pharmaceutical Industries Limited (IL) | 1979-05-30 | — | — | EP | claimed |