Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21376619 | 0.81 | HSD11B1 (0.47) | HSD11B1EPHX2NPC1RAB9AP2RX7 | |
| SCHEMBL24105897 | 0.76 | HSD11B1 (0.42) | HSD11B1EPHX2NPC1RAB9AL3MBTL1 | |
| SCHEMBL27643099 | 0.76 | ALDH1A1 (0.43) | HSD11B1EPHX2NPC1RAB9AP2RX7 | |
| SCHEMBL7719165 | 0.76 | HSD11B1 (0.42) | HSD11B1EPHX2 | |
| SCHEMBL8556476 | 0.76 | HSD11B1 (0.43) | HSD11B1EPHX2NPC1RAB9AL3MBTL1 | |
| SCHEMBL11440486 | 0.75 | HSD11B1 (0.55) | HSD11B1EPHX2P2RX7L3MBTL1CXCR3 | |
| SCHEMBL13609189 | 0.74 | KMT2A (0.47) | HSD11B1EPHX2NPC1RAB9AL3MBTL1 | |
| SCHEMBL20660478 | 0.72 | CYP2D6 (0.39) | CYP2D6 | |
| SCHEMBL19280968 | 0.72 | CYP2D6 (0.39) | CYP2D6 | |
| SCHEMBL20660476 | 0.72 | CYP2D6 (0.39) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426523-A | Preparation of 1-amino-1,3,5-triazine-2,4(1H, 3H)-diones | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-17 | — | — | US | disclosed |