SCHEMBL1144067

SCHEMBL1144067

C[SiH](C)C1=CCCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3675328 0.78 HDAC4 (0.38)
SCHEMBL5005559 0.69 ALDH1A1 (0.32)
SCHEMBL9863103 0.65 TYMP (0.42)
SCHEMBL5013024 0.65 HDAC3 (0.33)
SCHEMBL9296997 0.64
SCHEMBL3959 0.63
SCHEMBL28601700 0.63 HDAC4 (0.36)
SCHEMBL482644 0.63
SCHEMBL3297566 0.63
SCHEMBL296554 0.61 TYMP (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807758-B2 Siloxane polymer and method of producing siloxane polymer JNC CORPORATION (JP) 2023-11-07 US disclosed
US-20210238419-A1 SILOXANE POLYMER AND METHOD OF PRODUCING SILOXANE POLYMER JNC CORPORATION (JP) 2021-08-05 US disclosed
EP-2289974-B1 POLYHEDRAL OLIGOMERIC SILSESQUIOXANE IMAGE CONDITIONING COATING XEROX CORP (US) 2016-03-30 EP disclosed
US-8436166-B2 Amino-containing vinylsilane compounds and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-05-07 US disclosed
US-8268399-B2 Polyhedral oligomeric silsesquioxane image conditioning coating XEROX CORPORATION (US) 2012-09-18 US disclosed
US-20120010337-A1 Method For Treating A Carbon Allotrope XEROX CORPORATION (US) 2012-01-12 US disclosed
US-8084177-B2 Toners containing polyhedral oligomeric silsesquioxanes XEROX CORPORATION (US) 2011-12-27 US disclosed
US-7985523-B2 Toners containing polyhedral oligomeric silsesquioxanes XEROX CORPORATION (US) 2011-07-26 US disclosed
EP-2289974-A2 Polyhedral oligomeric silsesquioxane image conditioning coating Xerox Corporation (US) 2011-03-02 EP disclosed
US-20110045186-A1 Polyhedral Oligomeric Silsesquioxane Image Conditioning Coating XEROX CORPORATION (US) 2011-02-24 US disclosed
US-20100317852-A1 AMINO-CONTAINING VINYLSILANE COMPOUNDS AND MAKING METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-12-16 US disclosed
US-20100159376-A1 TONERS CONTAINING POLYHEDRAL OLIGOMERIC SILSESQUIOXANES XEROX CORPORATION (US) 2010-06-24 US disclosed
US-20100159375-A1 TONERS CONTAINING POLYHEDRAL OLIGOMERIC SILSESQUIOXANES XEROX CORPORATION (US) 2010-06-24 US disclosed
CN-101098911-A Ultraviolet transmissive polyhedral silsequioxane polymers MATSUSHITA ELECTRIC WORKS LTD (JP) 2008-01-02 CN disclosed