Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19781619 | 0.80 | CDC7 (0.41) | CDC7CDK2MAP3K14KMT2AROCK1 | |
| SCHEMBL15741202 | 0.75 | CDC7 (0.49) | CDC7CDK2MAP3K14MAPTNPC1 | |
| SCHEMBL15213048 | 0.73 | FGFR1 (0.53) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1607926 | 0.72 | NQO1 (0.52) | ALDH1A1NQO1LMNAMAPTMEN1 | |
| SCHEMBL1613814 | 0.72 | CDC7 (0.54) | CDC7CDK2MAP3K14MAPTROCK1 | |
| SCHEMBL6840530 | 0.70 | CYP11B2 (0.56) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL18358 | 0.70 | NQO1 (0.74) | ALDH1A1NQO1MAPTMEN1KMT2A | |
| SCHEMBL5780373 | 0.70 | L3MBTL1 (0.49) | NQO1LMNAMAPTMEN1KMT2A | |
| SCHEMBL31339915 | 0.69 | MAPT (0.44) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL29690879 | 0.69 | ROCK1 (0.50) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399509-B2 | Glucopyranoside derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-19 | — | — | US | disclosed |
| US-20110028414-A1 | GLUCOPYRANOSIDE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG | 2011-02-03 | — | — | US | disclosed |
| EP-2260051-A1 | GLUCOPYRANOSIDE DERIVATIVES | Merck Patent GmbH (DE) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009124638-A1 | GLUCOPYRANOSIDE DERIVATIVES | MERCK PATENT GMBH (DE) | 2009-10-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028414-A1 | GLUCOPYRANOSIDE DERIVATIVES | UGGT1, SLC5A1, SLC5A2 | CDC7 3913/4885CDK2 2256/4885MAP3K14 2304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.