Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MPL | P40238 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11436214 | 0.91 | RAB9A (0.41) | RAB9ALMNAHSD17B10MPLTSHR | |
| SCHEMBL11428114 | 0.91 | RAB9A (0.41) | RAB9ALMNAHSD17B10TSHRMCL1 | |
| SCHEMBL11438690 | 0.89 | TTR (0.43) | RAB9ALMNAHSD17B10TSHRMCL1 | |
| SCHEMBL11430401 | 0.85 | KCNMA1 (0.51) | RAB9ALMNATNFNOD1KCNMA1 | |
| SCHEMBL11425946 | 0.84 | RAB9A (0.43) | RAB9ALMNAHSD17B10MPLTSHR | |
| SCHEMBL11427943 | 0.84 | RAB9A (0.43) | RAB9ALMNAHSD17B10TSHRMRGPRX1 | |
| SCHEMBL11438814 | 0.84 | MPL (0.46) | RAB9ALMNAHSD17B10MPLTSHR | |
| SCHEMBL11431176 | 0.83 | KCNMA1 (0.54) | RAB9ALMNATNFNOD1KCNMA1 | |
| SCHEMBL11425885 | 0.82 | KMT2A (0.41) | RAB9ALMNAHSD17B10TSHRMCL1 | |
| SCHEMBL11440925 | 0.82 | MEN1 (0.41) | RAB9AHSD17B10MPLNPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |