Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 9/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.38 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.38 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.38 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL11428528 | 0.97 | MPL (0.43) | MPLKDM4EMEN1KMT2ALMNA | |
| SCHEMBL11439417 | 0.91 | MPL (0.46) | MPLKDM4EMEN1KMT2ALMNA | |
| SCHEMBL11438825 | 0.91 | MEN1 (0.41) | MPLKDM4EMEN1KMT2ALMNA | |
| SCHEMBL11439444 | 0.89 | TTR (0.43) | MPLKDM4EMEN1KMT2AHSD17B10 | |
| Acetic Acid SCHEMBL11425024 | 0.88 | MPL (0.43) | MPLKDM4EMEN1KMT2ALMNA | |
| SCHEMBL11430336 | 0.85 | KCNMA1 (0.48) | MPLKDM4EMEN1KMT2ALMNA | |
| SCHEMBL11435261 | 0.84 | AURKA (0.44) | KDM4EMEN1KMT2ALMNATSHR | |
| SCHEMBL11440926 | 0.84 | RAB9A (0.41) | MPLKDM4EMEN1KMT2ALMNA | |
| SCHEMBL11428526 | 0.84 | KDM4E (0.38) | MPLKDM4EMEN1KMT2ALMNA | |
| SCHEMBL11429460 | 0.83 | KMT2A (0.42) | KDM4EMEN1KMT2ALMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |