Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441314 | 0.86 | BRD4 (0.52) | BRD4ALDH1A1HSD17B10CREBBPKDM4E | |
| SCHEMBL11554573 | 0.84 | ALDH1A1 (0.48) | BRD4ALDH1A1MAPK1HSD17B10CREBBP | |
| SCHEMBL11547644 | 0.82 | BRD4 (0.48) | BRD4ALDH1A1HSD17B10CREBBPKDM4E | |
| SCHEMBL11178194 | 0.80 | BRD4 (0.40) | BRD4ALDH1A1HSD17B10SMN1; SMN2MAOB | |
| SCHEMBL11553976 | 0.79 | BRD4 (0.46) | BRD4ALDH1A1HSD17B10CREBBPKDM4E | |
| SCHEMBL11428173 | 0.79 | BRD4 (0.40) | BRD4ALDH1A1MAPK1HSD17B10CREBBP | |
| SCHEMBL11549547 | 0.78 | BRD4 (0.44) | BRD4ALDH1A1HSD17B10CREBBPKDM4E | |
| SCHEMBL11547968 | 0.77 | BRD9 (0.42) | ALDH1A1HSD17B10KDM4ESMN1; SMN2MAOB | |
| SCHEMBL11428886 | 0.77 | ALDH1A1 (0.36) | BRD4ALDH1A1MAPK1HSD17B10CREBBP | |
| SCHEMBL11554969 | 0.76 | BRD4 (0.43) | BRD4LMNAMAPTPTGS2MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |