Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11458087 | 0.98 | EPHX2 (0.34) | EPHX2CXCR3HSD11B1TDP1KMT2A | |
| SCHEMBL11442979 | 0.78 | EPHX2 (0.37) | EPHX2CXCR3HSD11B1TDP1ALDH1A1 | |
| SCHEMBL11442077 | 0.76 | CXCR3 (0.38) | CXCR3HSD11B1 | |
| Hydrochloric Acid SCHEMBL11458089 | 0.74 | CXCR3 (0.37) | CXCR3HSD11B1LMNASMN1; SMN2 | |
| SCHEMBL11442309 | 0.72 | HSD11B1 (0.41) | EPHX2HSD11B1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11449230 | 0.71 | HSD11B1 (0.40) | EPHX2HSD11B1KMT2ASMN1; SMN2 | |
| SCHEMBL11156387 | 0.70 | HSD11B1 (0.40) | EPHX2CXCR3HSD11B1ALDH1A1LMNA | |
| SCHEMBL1420785 | 0.69 | EPHX1 (0.38) | EPHX2CXCR3HSD11B1TDP1 | |
| Hydrochloric Acid SCHEMBL11152826 | 0.68 | HSD11B1 (0.39) | EPHX2CXCR3HSD11B1ALDH1A1LMNA | |
| SCHEMBL11442301 | 0.68 | EPHX2 (0.39) | EPHX2CXCR3HSD11B1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202892-A | FUNGICIDES, VIRICIDES, ANTIPROTOZOA AGENTS, PARKINSON'S DISEASE | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1980-05-13 | — | — | US | claimed |
| EP-0002065-A1 | Methyladamantyl hydrazines, their pharmaceutically acceptable salts and pharmaceutical compositions containing them | Teva Pharmaceutical Industries Limited (IL) | 1979-05-30 | — | — | EP | claimed |
| US-4202892-A | FUNGICIDES, VIRICIDES, ANTIPROTOZOA AGENTS, PARKINSON'S DISEASE | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1980-05-13 | — | — | US | disclosed |
| EP-0002065-A1 | Methyladamantyl hydrazines, their pharmaceutically acceptable salts and pharmaceutical compositions containing them | Teva Pharmaceutical Industries Limited (IL) | 1979-05-30 | — | — | EP | disclosed |