Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11458027 | 0.98 | EPHX2 (0.38) | EPHX2CXCR3L3MBTL1NPSR1FUCA1 | |
| SCHEMBL11156708 | 0.74 | EPHX2 (0.47) | EPHX2L3MBTL1NPSR1LMNASMN1; SMN2 | |
| SCHEMBL17352418 | 0.74 | LMNA (0.55) | EPHX2L3MBTL1NPSR1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11153601 | 0.73 | EPHX2 (0.46) | EPHX2L3MBTL1NPSR1LMNASMN1; SMN2 | |
| SCHEMBL11442077 | 0.73 | CXCR3 (0.38) | CXCR3L3MBTL1HSD11B1 | |
| Hydrochloric Acid SCHEMBL11458089 | 0.71 | CXCR3 (0.37) | CXCR3LMNASMN1; SMN2HSD11B1 | |
| SCHEMBL191696 | 0.70 | HSD11B1 (0.38) | EPHX2L3MBTL1NPSR1HSD11B1 | |
| SCHEMBL190682 | 0.69 | HSD11B1 (0.41) | EPHX2CXCR3L3MBTL1NPSR1HSD11B1 | |
| SCHEMBL7099148 | 0.69 | EPHX2 (0.41) | EPHX2L3MBTL1NPSR1HSD11B1 | |
| SCHEMBL11442117 | 0.68 | EPHX2 (0.35) | EPHX2CXCR3LMNASMN1; SMN2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202892-A | FUNGICIDES, VIRICIDES, ANTIPROTOZOA AGENTS, PARKINSON'S DISEASE | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1980-05-13 | — | — | US | claimed |
| EP-0002065-A1 | Methyladamantyl hydrazines, their pharmaceutically acceptable salts and pharmaceutical compositions containing them | Teva Pharmaceutical Industries Limited (IL) | 1979-05-30 | — | — | EP | claimed |
| US-4202892-A | FUNGICIDES, VIRICIDES, ANTIPROTOZOA AGENTS, PARKINSON'S DISEASE | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1980-05-13 | — | — | US | disclosed |
| EP-0002065-A1 | Methyladamantyl hydrazines, their pharmaceutically acceptable salts and pharmaceutical compositions containing them | Teva Pharmaceutical Industries Limited (IL) | 1979-05-30 | — | — | EP | disclosed |