Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.89 |
| ▸ | CA4 | P22748 | 2/20 | 0.89 |
| ▸ | CES1 | P23141 | 3/20 | 0.55 |
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 11/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL9824758 | 0.97 | CA2 (0.84) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL11789341 | 0.97 | CA2 (0.94) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL188041 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL394354 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL12476955 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL944537 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL1445056 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL20570232 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL20570059 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL4525348 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1874 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260008882-A1 | SILANE-TERMINATED POLYMERS | MERZ + BENTELI AG (CH) | 2026-01-08 | — | — | US | claimed |
| US-12448536-B2 | Nano metal paste, and preparation and application thereof | GUANGDONG UNIVERSITY OF TECHNOLOGY (CN) | 2025-10-21 | — | — | US | claimed |
| EP-4554998-A1 | SILANE-TERMINATED POLYMERS | MERZ + BENTELI AG (CH) | 2025-05-21 | — | — | EP | claimed |
| US-12263198-B1 | Compositions and methods of improving ruminant performance | RALCO NUTRITION, INC. (US) | 2025-04-01 | — | — | US | claimed |
| CN-119433594-A | Lignin derived carbon-alloy-metal oxide heterojunction catalyst and preparation method thereof | 广西大学 | 2025-02-14 | — | — | CN | claimed |
| CN-119371582-A | Polybutadiene composite rubber and preparation method thereof, rubber composition and application thereof | 中国石油化工股份有限公司 | 2025-01-28 | — | — | CN | claimed |
| CN-115672329-B | Co-series eggshell catalyst and preparation method thereof | 中国石油大学(华东) | 2024-07-26 | — | — | CN | claimed |
| CN-116403757-B | Nano metal powder slurry and preparation method and application thereof | 广东工业大学 | 2024-07-02 | — | — | CN | claimed |
| CN-118022775-A | Catalyst for catalytic oxidative cracking of hydrogen sulfide and simultaneous production of hydrogen | 内斯特化学技术股份有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-117924070-A | Method for preparing benzoic acid by catalyzing toluene oxidation | 湖南松源生物科技有限公司 | 2024-04-26 | — | — | CN | claimed |
| US-4459394-A | CATALYST, AMMONIUM SALT OF UNSATURATED MONOCARBOXYLIC ACID | THE STANDARD OIL COMPANY (US) | 1984-07-10 | — | — | US | claimed |
| US-4438018-A | REACTING A CYCLIC NITROGEN CONTAINING VINYL MONOMER AND ESTER OF AN UNSATURATED DIBASIC ACID | THE CELOTEX CORPORATION (US) | 1984-03-20 | — | — | US | claimed |
| EP-0011401-B1 | PROCESS FOR THE PRODUCTION OF HEXAMETHYLENEDIAMINE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-06-01 | — | — | EP | claimed |
| US-4340685-A | SYNDIOTACTIC POLYMERIZATION CATALYST | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1982-07-20 | — | — | US | claimed |
| US-4339608-A | BUTANOL AND BUTANAL, COBALT, IODINE | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-07-13 | — | — | US | claimed |
| EP-0039756-A2 | Preparation of polyoxyalkylene surfactants for the stabilisation of phenolic foam, optionally in the presence of a metal catalyst | Celotex Corporation (US) | 1981-11-18 | — | — | EP | claimed |
| US-4230882-A | OXIDATION OF P-XYLENE WITH COBALT-MANGANESE-BROMINE CATALYST SYSTEM | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1980-10-28 | — | — | US | claimed |
| EP-0011401-A2 | Process for the production of hexamethylenediamine | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-05-28 | — | — | EP | claimed |
| US-4153767-A | COBALT COMPOUND-ORGANOALUMINUM COMPOUND CATALYST | UBE INDUSTRIES LIMITED (JP) | 1979-05-08 | — | — | US | claimed |
| US-4001187-A | CONTINUOUS PROCESSING | KANEBO, LTD. (JA) | 1977-01-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260008882-A1 | SILANE-TERMINATED POLYMERS | EPCAM, HBS1L, CDH1 | CA2 879/4885CA4 1592/4885CES1 2004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.