Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11445047 | 0.88 | POLB (0.63) | POLBKMT2AMEN1RCE1 | |
| SCHEMBL11543143 | 0.78 | POLB (0.58) | POLBKMT2AMEN1RCE1 | |
| SCHEMBL17211707 | 0.70 | MEN1 (0.71) | POLBKMT2AMEN1 | |
| SCHEMBL15832516 | 0.65 | GPR35 (0.72) | POLBKMT2AMEN1 | |
| SCHEMBL2643933 | 0.64 | TSHR (0.43) | POLB | |
| SCHEMBL11502584 | 0.62 | KMT2A (0.43) | KMT2AMEN1 | |
| SCHEMBL11546288 | 0.60 | ABCB11 (0.67) | POLBKMT2AMEN1 | |
| SCHEMBL9847122 | 0.60 | GPR35 (0.54) | POLBKMT2AMEN1 | |
| SCHEMBL11246518 | 0.60 | GPR35 (0.63) | KMT2AMEN1 | |
| SCHEMBL11310597 | 0.60 | ABCB11 (0.83) | POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4238606-A | ANTIALLERGANS | FISONS LIMITED (GB) | 1980-12-09 | — | — | US | disclosed |