Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11543143 | 0.89 | POLB (0.58) | POLBPDE4DMEN1KMT2ARCE1 | |
| SCHEMBL11444906 | 0.88 | POLB (0.54) | POLBMEN1KMT2ARCE1 | |
| SCHEMBL27949359 | 0.67 | HSP90AA1 (0.57) | POLBPDE4DMEN1KMT2A | |
| SCHEMBL11502584 | 0.64 | KMT2A (0.43) | MEN1KMT2ARAB9A | |
| SCHEMBL17211707 | 0.64 | MEN1 (0.71) | POLBMEN1KMT2A | |
| SCHEMBL7220811 | 0.64 | CA2 (0.54) | POLBMEN1KMT2ARAB9A | |
| SCHEMBL7228890 | 0.64 | KDM4E (0.60) | MEN1KMT2ARAB9A | |
| SCHEMBL30495897 | 0.64 | PDE4D (0.48) | POLBPDE4DPDE5A | |
| SCHEMBL4220888 | 0.63 | PDE5A (1.00) | POLBPDE4DMEN1KMT2APDE5A | |
| SCHEMBL29363725 | 0.63 | PDE5A (1.00) | POLBPDE4DMEN1KMT2APDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4238606-A | ANTIALLERGANS | FISONS LIMITED (GB) | 1980-12-09 | — | — | US | claimed |
| US-4238606-A | ANTIALLERGANS | FISONS LIMITED (GB) | 1980-12-09 | — | — | US | disclosed |
| US-4159273-A | ANTIALLERGENS, ANTIHISTAMINES | FISONS LIMITED (GB) | 1979-06-26 | — | — | US | disclosed |