Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 7/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 7/20 | 0.43 |
| ▸ | RELA | Q04206 | 7/20 | 0.43 |
| ▸ | OSBP | P22059 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5743160 | 0.69 | CYP3A4 (0.62) | MEN1KMT2A | |
| SCHEMBL14098879 | 0.69 | COXFA4 (0.64) | HSP90AA1COXFA4KMT2A | |
| SCHEMBL3456379 | 0.69 | COXFA4 (0.64) | HSP90AA1COXFA4 | |
| SCHEMBL3456476 | 0.69 | COXFA4 (0.77) | HSP90AA1COXFA4 | |
| SCHEMBL27981979 | 0.68 | PDE4D (0.47) | HSP90AA1POLBPDE4DNFKB1NFKB2 | |
| SCHEMBL2913406 | 0.67 | LMNA (0.57) | NFKB1PTGS2 | |
| SCHEMBL2307800 | 0.67 | PTGS2 (0.55) | POLBPTGS2MEN1KMT2A | |
| SCHEMBL23423090 | 0.67 | HPGD (0.51) | HSP90AA1POLBPDE4DMEN1KMT2A | |
| SCHEMBL11445047 | 0.67 | POLB (0.63) | POLBPDE4DMEN1KMT2A | |
| SCHEMBL11156631 | 0.67 | BCHE (0.44) | HSP90AA1POLBCOXFA4PDE4DKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103524472-B | Phenolic compound, and preparation method and application thereof | YUNNAN TOBACCO SCI RES INST | 2015-06-24 | — | — | CN | disclosed |
| CN-103524472-A | Phenolic compound, and preparation method and application thereof | YUNNAN TOBACCO SCI RES INST | 2014-01-22 | — | — | CN | disclosed |