Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 11/20 | 0.41 |
| ▸ | CRY2 | Q49AN0 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vincantril SCHEMBL2734148 | 0.85 | HSD17B10 (0.39) | HSD17B10CYP1A2CYP2D6MEN1TP53 | |
| SCHEMBL10836067 | 0.82 | HSD17B10 (0.50) | PER2HSD17B10CYP1A2CYP2D6MEN1 | |
| SCHEMBL11445324 | 0.74 | MAPKAPK2 (0.38) | PER2CRY2HTR1AMAPKAPK2 | |
| Hydrochloric Acid SCHEMBL11469730 | 0.73 | HSD17B10 (0.60) | PER2HSD17B10CYP1A2CYP2D6MEN1 | |
| SCHEMBL16602554 | 0.67 | MAPKAPK2 (0.55) | PER2CRY2HSD17B10MAPKAPK2 | |
| SCHEMBL11193303 | 0.64 | HSD17B10 (0.45) | PER2HSD17B10CYP1A2CYP2D6MEN1 | |
| Hydrochloric Acid SCHEMBL11191037 | 0.63 | HSD17B10 (0.47) | PER2HSD17B10CYP1A2CYP2D6MEN1 | |
| SCHEMBL10959627 | 0.61 | HTR6 (0.44) | — | |
| SCHEMBL25685401 | 0.59 | SIGMAR1 (0.43) | — | |
| SCHEMBL17945910 | 0.59 | MAPKAPK2 (0.52) | HSD17B10KDM4EMAPKAPK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190657-A | ANTI-ANOXIA AND PSYCHOTROPIC ACTIVITY | SYNTHELABO (FR) | 1980-02-26 | — | — | US | claimed |