Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | PER2 | O15055 | 9/20 | 0.35 |
| ▸ | CRY2 | Q49AN0 | 7/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11445075 | 0.85 | MEN1 (0.37) | MAPKAPK2HTR2AHTR2CCA1CA2 | |
| SCHEMBL11445321 | 0.74 | PER2 (0.41) | MAPKAPK2PER2CRY2HTR1A | |
| SCHEMBL11455502 | 0.72 | MAPKAPK2 (0.41) | MAPKAPK2HTR2AHTR2CHTR6PTGDR2 | |
| SCHEMBL11463557 | 0.69 | MEN1 (0.33) | MAPKAPK2PTGDR2 | |
| SCHEMBL16602554 | 0.69 | MAPKAPK2 (0.55) | MAPKAPK2PER2CRY2HTR6PTGDR2 | |
| SCHEMBL11453418 | 0.65 | PDE1A (0.41) | HTR2BCA1CA2CA4CA7 | |
| Hydrochloric Acid SCHEMBL11272723 | 0.65 | MAPKAPK2 (0.73) | MAPKAPK2HTR2AHTR2CHTR2BADRB1 | |
| SCHEMBL6234161 | 0.64 | MAPKAPK2 (0.59) | MAPKAPK2 | |
| SCHEMBL6240818 | 0.62 | MAPKAPK2 (0.56) | MAPKAPK2HTR6PTGDR2 | |
| SCHEMBL17945910 | 0.62 | MAPKAPK2 (0.52) | MAPKAPK2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4190657-A | ANTI-ANOXIA AND PSYCHOTROPIC ACTIVITY | SYNTHELABO (FR) | 1980-02-26 | — | — | US | disclosed |