Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903251 | 0.77 | PDE4D (0.51) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL8901601 | 0.77 | PDE4D (0.51) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL8901597 | 0.77 | PDE4D (0.51) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL11623420 | 0.73 | KDM4E (0.51) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL11599490 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL11599493 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL11599487 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL11806972 | 0.72 | ALDH1A1 (0.60) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL11807287 | 0.72 | ALDH1A1 (0.60) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL7671306 | 0.72 | PDE4D (0.62) | KDM4EALDH1A1HKDC1TDP1SAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4187236-A | 7-Oxabicycloheptane compounds | E. R. SQUIBB & SONS, INC. (US) | 1980-02-05 | — | — | US | disclosed |