Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11445361 | 0.87 | FFAR1 (0.46) | ALDH1A1MAPTFFAR1EGLN1 | |
| SCHEMBL11445412 | 0.87 | PTGS2 (0.47) | ALDH1A1KMT2AMAPTMEN1L3MBTL1 | |
| SCHEMBL11464626 | 0.87 | GRIA4 (0.39) | ALDH1A1MAPTTDP1L3MBTL1FFAR1 | |
| SCHEMBL11445250 | 0.86 | SRD5A2 (0.42) | KMT2AMAPTMEN1CNR2PRNP | |
| SCHEMBL11445292 | 0.85 | ALDH1A1 (0.45) | ALDH1A1MAPTL3MBTL1FFAR1TP53 | |
| SCHEMBL11497744 | 0.85 | ALOX5 (0.47) | ALDH1A1KMT2AMEN1FFAR1TP53 | |
| SCHEMBL11445807 | 0.85 | HPGD (0.40) | SLC6A3ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL11446156 | 0.84 | HAO1 (0.41) | SLC6A4ALDH1A1GAA | |
| SCHEMBL11445878 | 0.83 | FFAR1 (0.49) | SLC6A4SLC6A3ALDH1A1KMT2AMAPT | |
| SCHEMBL11464804 | 0.82 | AKR1C3 (0.41) | SLC6A4SLC6A3ALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4191776-A | ANTITHROMBOTICS, ANTICHOLESTEREMICS, ANTICOAGULANTS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-03-04 | — | — | US | disclosed |
| US-3993683-A | ANTITHROMBOTIC, ANTICHOLESTEREMICS, ANTICOAGULANTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-11-23 | — | — | US | disclosed |