Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11465300 | 0.92 | HTR7 (0.47) | HTR7POLBGFERHSD17B10KMT2A | |
| SCHEMBL11454852 | 0.88 | HTR7 (0.56) | HTR7POLBGFERHSD17B10DRD4 | |
| SCHEMBL11447087 | 0.88 | HTR7 (0.51) | HTR7POLBGFERHSD17B10KMT2A | |
| SCHEMBL11447099 | 0.87 | HTR7 (0.52) | HTR7POLBGFERHSD17B10KMT2A | |
| SCHEMBL11456795 | 0.87 | POLB (0.52) | HTR7POLBGFERKMT2AMEN1 | |
| SCHEMBL11446750 | 0.86 | POLB (0.47) | HTR7POLBGFERHSD17B10KMT2A | |
| SCHEMBL11448339 | 0.86 | HTR6 (0.54) | HTR7POLBGFERKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11447560 | 0.86 | HTR7 (0.51) | HTR7POLBGFERHSD17B10KMT2A | |
| SCHEMBL11446172 | 0.86 | DRD4 (0.56) | HTR7POLBGFERKMT2AMEN1 | |
| SCHEMBL11446759 | 0.83 | HTR7 (0.47) | HTR7POLBGFERHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4205173-A | 1-Heterocyclic alkyl-1,2,3,4-tetrahydroquinazolinones and analgesic intermediates thereof | PENNWALT CORPORATION (US) | 1980-05-27 | — | — | US | disclosed |
| US-4085107-A | ANALGESICS | PENNWALT CORPORATION (US) | 1978-04-18 | — | — | US | disclosed |
| US-4060526-A | 1-Heterocyclic alkyl-1,2,3,4-tetrahydroquinazolinones and analgesic intermediates thereof | PENNWALT CORPORATION (US) | 1977-11-29 | — | — | US | disclosed |