Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11440114 | 0.87 | HRH3 (0.48) | HTTSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL11438433 | 0.85 | MEN1 (0.40) | HTTSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL11453860 | 0.82 | HTT (0.49) | HTTSMN1; SMN2L3MBTL1MEN1KMT2A | |
| SCHEMBL11446220 | 0.81 | CYP4F2 (0.47) | HTTSMN1; SMN2L3MBTL1MEN1KMT2A | |
| SCHEMBL11469822 | 0.78 | NPC1 (0.52) | HTTSMN1; SMN2L3MBTL1MEN1KMT2A | |
| SCHEMBL11525477 | 0.77 | POLB (0.48) | HTTSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL11496018 | 0.75 | HDAC3 (0.56) | HTTMEN1KMT2APOLBNFKB1 | |
| SCHEMBL11528144 | 0.71 | CYP4F2 (0.47) | HTTSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL11545033 | 0.69 | ADAMTS5 (0.53) | HTTSMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL11530821 | 0.69 | LMNA (0.47) | HTTMEN1KMT2APOLBNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019955-A1 | Benzofurancarboxylic acid derivatives, their preparation and their inclusion in lipogenesis inhibiting compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1980-12-10 | — | — | EP | disclosed |
| US-4205080-A | LIPOGENESIS INHIBITORS | SHELL OIL COMPANY (US) | 1980-05-27 | — | — | US | disclosed |