Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11440114 | 0.90 | HRH3 (0.48) | POLBHDAC3HDAC1HDAC2NFKB1 | |
| SCHEMBL11530821 | 0.86 | LMNA (0.47) | POLBHDAC3HDAC1HDAC2NFKB1 | |
| SCHEMBL11527877 | 0.84 | PPARG (0.52) | NFKB1NFKB2RELARAB9AHTT | |
| SCHEMBL11528144 | 0.82 | CYP4F2 (0.47) | POLBHDAC3HDAC1HDAC2NFKB1 | |
| SCHEMBL11527702 | 0.82 | KMT2A (0.49) | POLBNFKB1NFKB2RELALMNA | |
| SCHEMBL11526092 | 0.80 | HDAC3 (0.49) | HDAC3HDAC1HDAC2NFKB1NFKB2 | |
| SCHEMBL29587603 | 0.80 | HDAC3 (0.49) | HDAC3HDAC1HDAC2NFKB1NFKB2 | |
| SCHEMBL11545033 | 0.80 | ADAMTS5 (0.53) | POLBLMNANPC1RAB9AKMT2A | |
| SCHEMBL29586727 | 0.80 | NFKB1 (0.50) | HDAC3HDAC1HDAC2NFKB1NFKB2 | |
| SCHEMBL11527340 | 0.79 | CYP4F2 (0.39) | HDAC3HDAC1HDAC2NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178380-A | LIPOGENSIS INHIBITORS | SHELL OIL COMPANY (US) | 1979-12-11 | — | — | US | disclosed |