Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550114 | 0.96 | CNR2 (0.39) | MEN1KMT2ASLC6A2SLC6A4TSHR | |
| SCHEMBL11446729 | 0.90 | BCL2A1 (0.37) | MEN1KMT2ACNR2SIGMAR1KCNH2 | |
| SCHEMBL11547950 | 0.87 | NPC1 (0.38) | MEN1KMT2ACNR2SIGMAR1BCL2A1 | |
| SCHEMBL11446524 | 0.85 | MEN1 (0.40) | MEN1KMT2ASLC6A2SLC6A4TSHR | |
| Ethylbenzene SCHEMBL11570518 | 0.84 | AGER (0.38) | MEN1KMT2ASIGMAR1ALDH1A1LMNA | |
| SCHEMBL11434897 | 0.84 | MEN1 (0.39) | MEN1KMT2ASLC6A2SLC6A4TSHR | |
| SCHEMBL11447042 | 0.84 | MEN1 (0.39) | MEN1KMT2ASLC6A2SLC6A4TSHR | |
| SCHEMBL11456610 | 0.81 | ALDH1A1 (0.34) | MEN1KMT2ACNR2SIGMAR1KCNH2 | |
| Ethylbenzene SCHEMBL11337300 | 0.81 | AGER (0.40) | MEN1KMT2ACNR2SIGMAR1ALDH1A1 | |
| SCHEMBL11550110 | 0.80 | MEN1 (0.41) | MEN1KMT2ATSHRSIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204003-A | N-(2-Aminocyclopentyl)-N-alkanoylanilides as CNS anti-depressants | THE UPJOHN COMPANY (US) | 1980-05-20 | — | — | US | disclosed |