Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.38 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11447011 | 1.00 | TRPA1 (0.42) | TRPA1LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL11468793 | 0.95 | LMNA (0.46) | TRPA1LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL11468794 | 0.95 | LMNA (0.46) | TRPA1LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL11570582 | 0.80 | SSTR3 (0.38) | TRPA1LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL11570584 | 0.80 | SSTR3 (0.38) | TRPA1LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL11450448 | 0.80 | SLC6A4 (0.49) | TRPA1LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL11446427 | 0.80 | TRPA1 (0.42) | TRPA1LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL11446423 | 0.80 | TRPA1 (0.42) | TRPA1LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL11443800 | 0.80 | SLC6A4 (0.49) | TRPA1LMNASMN1; SMN2HTTMEN1 | |
| SCHEMBL11443799 | 0.80 | SLC6A4 (0.49) | TRPA1LMNASMN1; SMN2HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204003-A | N-(2-Aminocyclopentyl)-N-alkanoylanilides as CNS anti-depressants | THE UPJOHN COMPANY (US) | 1980-05-20 | — | — | US | disclosed |
| US-4156015-A | N-(2-Aminocyclopentyl)acylanilides and treating depression | THE UPJOHN COMPANY (US) | 1979-05-22 | — | — | US | disclosed |