Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11468793 | 1.00 | LMNA (0.46) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL11447011 | 0.95 | TRPA1 (0.42) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL11447010 | 0.95 | TRPA1 (0.42) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL11334450 | 0.81 | MAPT (0.41) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL11334447 | 0.81 | MAPT (0.41) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL11334977 | 0.81 | SLC6A4 (0.51) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL11480574 | 0.81 | MEN1 (0.46) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL11334975 | 0.81 | SLC6A4 (0.51) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL11480572 | 0.81 | MEN1 (0.46) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL11479971 | 0.80 | SIGMAR1 (0.45) | LMNAMEN1KMT2AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4199589-A | N-(2-Aminocycloheptyl)acylanilides and methods to treat depression | SZMUSZKOVICZ JACOB (US) | 1980-04-22 | — | — | US | disclosed |
| US-4172898-A | N-(2-aminocycloheptyl)acylanilides | THE UPJOHN COMPANY (US) | 1979-10-30 | — | — | US | disclosed |
| US-4159339-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4156014-A | N-(2-aminocycloheptyl)alkanoylanilides and in the treatment of depression | THE UPJOHN COMPANY (US) | 1979-05-22 | — | — | US | disclosed |