Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | RECQL | P46063 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | PARP1 | P09874 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.61 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.58 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.58 |
| ▸ | UNG | P13051 | 1/20 | 0.53 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzaldehyde SCHEMBL27768995 | 0.86 | ALDH1A1 (0.74) | MAPTTDP1RECQLTSHRPOLB | |
| Benzaldehyde SCHEMBL10734023 | 0.86 | ALDH1A1 (0.74) | MAPTTDP1RECQLTSHRPOLB | |
| Benzaldehyde SCHEMBL12819205 | 0.84 | ALDH1A1 (0.70) | MAPTTDP1RECQLTSHRPOLB | |
| SCHEMBL317442 | 0.84 | PARP10 (0.77) | MAPTTDP1RECQLTSHRPOLB | |
| Benzamide SCHEMBL3541486 | 0.84 | PARP1 (0.80) | MAPTTDP1RECQLTSHRPOLB | |
| Benzamide SCHEMBL8772889 | 0.84 | PARP1 (0.80) | MAPTTDP1RECQLTSHRPOLB | |
| Benzamide SCHEMBL1332331 | 0.83 | — | — | |
| Benzamide SCHEMBL29618402 | 0.83 | — | — | |
| SCHEMBL21755166 | 0.83 | PARP1 (1.00) | MAPTTDP1RECQLTSHRPOLB | |
| Benzamide SCHEMBL30112947 | 0.83 | PARP1 (1.00) | MAPTTDP1RECQLTSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4205173-A | 1-Heterocyclic alkyl-1,2,3,4-tetrahydroquinazolinones and analgesic intermediates thereof | PENNWALT CORPORATION (US) | 1980-05-27 | — | — | US | disclosed |
| US-4060526-A | 1-Heterocyclic alkyl-1,2,3,4-tetrahydroquinazolinones and analgesic intermediates thereof | PENNWALT CORPORATION (US) | 1977-11-29 | — | — | US | disclosed |