SCHEMBL317442

SCHEMBL317442

NC(=O)c1ccc(C=O)cc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 5/20 0.77
PARP3 Q9Y6F1 1/20 0.77
ALDH1A1 P00352 3/20 0.62
PARP4 Q9UKK3 2/20 0.50
PARP1 P09874 2/20 0.50
TSHR P16473 2/20 0.50
HSD17B10 Q99714 2/20 0.50
PARP15 Q460N3 2/20 0.50
KMT2A Q03164 1/20 0.50
PARP14 Q460N5 1/20 0.50
PARP16 Q8N5Y8 1/20 0.50
PARP11 Q9NR21 1/20 0.50
POLB P06746 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAPT P10636 1/20 0.50
CYP2C19 P33261 1/20 0.50
RECQL P46063 1/20 0.50
BLM P54132 1/20 0.50
PMP22 Q01453 1/20 0.50
TDP1 Q9NUW8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19048679 0.93 PARP10 (0.69) PARP10PARP3ALDH1A1PARP4PARP15
Terephthalamic Acid SCHEMBL27598300 0.91 ALDH1A1 (0.79) PARP10PARP3ALDH1A1PARP4PARP1
SCHEMBL3632726 0.91 PARP10 (0.67) PARP10PARP3ALDH1A1PARP4PARP1
SCHEMBL754740 0.88 PARP10 (1.00) PARP10PARP3ALDH1A1PARP4PARP1
SCHEMBL28209521 0.84 PARP10 (0.59) PARP10PARP3ALDH1A1PARP4PARP1
Benzamide SCHEMBL11447237 0.84 MAPT (0.70) PARP10PARP3ALDH1A1PARP1TSHR
SCHEMBL11833367 0.82 CYP2C19 (0.58) PARP10PARP3ALDH1A1PARP4PARP1
SCHEMBL11833372 0.82 CYP2C19 (0.58) PARP10PARP3ALDH1A1PARP4PARP1
SCHEMBL8583415 0.82 PARP10 (0.55) PARP10PARP3ALDH1A1PARP4PARP1
SCHEMBL9902871 0.81 PARP10 (0.55) PARP10PARP3ALDH1A1PARP4PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 430 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178649-B High-strength solvent-resistant plastic capable of being recycled in closed loop, preparation method and recycling method thereof 吉林大学 2025-02-07 CN claimed
CN-112649601-B Enzyme-labeled coupled secondary antibody and preparation method thereof 苏州百道医疗科技有限公司 2024-06-25 CN claimed
CN-116262976-B Electrochemical synthesis method of benzaldehyde derivative 国科大杭州高等研究院 2024-04-05 CN claimed
US-20220099661-A1 ELECTROCHEMILUMINESCENT LABELED PROBES FOR USE IN IMMUNOASSAY METHODS, METHODS USING SUCH AND KITS COMPRISING SAME MESO SCALE TECHNOLOGIES, LLC. 2022-03-31 US claimed
CN-114144422-A Electrochemiluminescence labeled probes for use in immunization methods, methods of using such probes, and kits comprising such probes 中尺度技术有限责任公司 2022-03-04 CN claimed
EP-3931201-A1 ELECTROCHEMILUMINESCENT LABELED PROBES FOR USE IN IMMUNOASSAY METHODS, METHODS USING SUCH AND KITS COMPRISING SAME Meso Scale Technologies, LLC (US) 2022-01-05 EP claimed
EP-3272864-A1 SOLID-PHASE IMMOBILIZATION OF MICROBIAL TRANSGLUTAMINASE MTG ON MICROBEADS FOR PROTEIN CONJUGATION PAUL SCHERRER INSTITUT (CH) 2018-01-24 EP claimed
CN-103130735-B Indole amine 2,3-dioxygenase regulator and usage thereof 因塞特控股公司 2016-08-03 CN claimed
US-9067982-B2 Compositions and methods for redox modulated proteins VEDAMOORTHY SRIKANTH (US) 2015-06-30 US claimed
CN-103183961-B Solution of polyamic acid resin containing interpenetrating network polymer and polyimide metal laminate IND TECH RES INST 2015-03-04 CN claimed
CN-103183961-A Solution of polyamic acid resin containing interpenetrating network polymer and polyimide metal laminate IND TECH RES INST 2013-07-03 CN claimed
CN-103130735-A Modulators of indoleamine 2,3-dioxygenase and methods of using the same INCYTE CORP 2013-06-05 CN claimed
WO-2013004716-A1 PEPTIDE BEADS UNIVERSITÄT BASEL (CH) 2013-01-10 WO claimed
WO-2008133344-A2 PIPERIDINE DERIVATIVE AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-11-06 WO claimed
US-20080275085-A1 Piperidine derivative and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-11-06 US claimed
CN-1768026-A 2-aryl-acetic acids, their derivatives and pharmaceutical compositions containing them DOMPE SPA (IT) 2006-05-03 CN claimed
US-4113759-A PIGMENTS FOR PAINTS, LACQUERS, INKS, PLASTICS HOECHST AKTIENGESELLSCHAFT (DE) 1978-09-12 US claimed
CN-122079899-A Application of pharmaceutical composition in preparation of medicines for preventing or treating diseases related to Sirttail 7 protein 2026-05-26 CN disclosed
EP-0001769-A1 Sulfur-containing esters of 1,4-dihydropyridine carboxylic acids, their preparation and pharmaceutical use BAYER AG (DE) 1979-05-16 EP disclosed
US-4044141-A CORONARY DILATING, SPASMOLYTIC, HYPOTENSIVE AGENTS BAYER AKTIENGESELLSCHAFT (DT) 1977-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220099661-A1 ELECTROCHEMILUMINESCENT LABELED PROBES FOR USE IN IMMUNOASSAY METHODS, METHODS USING SUCH AND KITS COMPRISING SAME ALPL, SHBG, GUSB PARP10 2369/4885PARP3 2230/4885ALDH1A1 99/4885
US-20080275085-A1 Piperidine derivative and use thereof TACR2, TACR1, PRLHR PARP10 2706/4885PARP3 3000/4885ALDH1A1 3412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.