Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | AHR | P35869 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441489 | 0.87 | KMT2A (0.64) | RAD52KMT2AMEN1MAPTPOLB | |
| SCHEMBL11447427 | 0.84 | FTO (0.66) | RAD52KMT2AMEN1MAPTPOLB | |
| SCHEMBL10717644 | 0.80 | FTO (0.49) | RAD52KMT2AMEN1MAPTPOLB | |
| SCHEMBL13707320 | 0.77 | FTO (0.61) | RAD52KMT2AMEN1MAPTPOLB | |
| SCHEMBL11433686 | 0.76 | MAPT (0.73) | RAD52KMT2AMEN1MAPTPOLB | |
| SCHEMBL11434790 | 0.76 | RAD52 (1.00) | RAD52KMT2AMEN1MAPTPOLB | |
| SCHEMBL11434901 | 0.76 | MAPT (0.69) | RAD52KMT2AMEN1MAPTPOLB | |
| SCHEMBL11447373 | 0.75 | TYMS (0.64) | MAPTLMNA | |
| SCHEMBL6272682 | 0.74 | MAPT (0.73) | RAD52KMT2AMEN1MAPTPOLB | |
| SCHEMBL11442040 | 0.74 | MAPT (0.73) | RAD52KMT2AMEN1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204063-A | ANTITUMOR AGENTS | LABORATORIOS MADE, S.A. (ES) | 1980-05-20 | — | — | US | disclosed |