SCHEMBL1144747

SCHEMBL1144747

C=C(C)c1ccc(OC(C)N)cc1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.44
KMT2A Q03164 2/20 0.41
MAPT P10636 2/20 0.36
MEN1 O00255 1/20 0.36
POLB P06746 2/20 0.34
GLA P06280 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
SCN5A Q14524 1/20 0.33
SCN2A Q99250 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ELANE P08246 2/20 0.32
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19886220 0.83 KMT2A (0.59) PARP10KMT2AMAPTMEN1POLB
SCHEMBL6689348 0.80 KMT2A (0.41) PARP10KMT2AMAPTMEN1POLB
SCHEMBL6691528 0.77 KMT2A (0.43) PARP10KMT2AMAPTMEN1POLB
SCHEMBL11577753 0.76 ACHE (0.46) PARP10KMT2AMAPTMEN1POLB
SCHEMBL11574352 0.76 PARP10 (0.75) PARP10KMT2APOLBGLA
SCHEMBL6694133 0.76 KMT2A (0.38) PARP10KMT2AMAPTMEN1POLB
SCHEMBL10704421 0.76 CYP1A2 (0.59) PARP10KMT2AMEN1HPGDKDM4E
SCHEMBL6697110 0.76 KMT2A (0.38) PARP10KMT2AMAPTMEN1POLB
SCHEMBL6689051 0.75 KMT2A (0.35) PARP10KMT2AMAPTPOLBKDM4E
SCHEMBL6694487 0.75 TSHR (0.37) KMT2AMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114616365-A Polymer-filled polyolefin fibers 帝斯曼知识产权资产管理有限公司 2022-06-10 CN disclosed
EP-2908937-B1 MICROSPHERES MERCK PATENT GMBH (DE) 2018-08-08 EP disclosed
US-9944778-B2 Microspheres MERCK PATENT GMBH (DE) 2018-04-17 US disclosed
US-20150259518-A1 MICROSPHERES MERCK PATENT GMBH (DE) 2015-09-17 US disclosed
EP-2908937-A2 MICROSPHERES Merck Patent GmbH (DE) 2015-08-26 EP disclosed
US-9050843-B2 Microsphere comprising a polymer core, a shell and an absorber MERCK PATENT GMBH (DE) 2015-06-09 US disclosed
WO-2014060099-A2 MICROSPHERES MERCK PATENT GMBH (DE) 2014-04-24 WO disclosed
US-20110034609-A1 MICROSPHERE COMPRISING A POLYMER CORE, A SHELL AND AN ABSORBER SUSONITY Commercial GmbH (DE) 2011-02-10 US disclosed
EP-2162293-B1 MICROSPHERE COMPRISING A POLYMER CORE, A SHELL AND AN ABSORBER MERCK PATENT GMBH (DE) 2010-10-20 EP disclosed
EP-2162293-A1 MICROSPHERE COMPRISING A POLYMER CORE, A SHELL AND AN ABSORBER Merck Patent GmbH (DE) 2010-03-17 EP disclosed
EP-1567595-B1 LASER WRITABLE COMPOSITION DSM IP ASSETS BV (NL) 2006-04-26 EP disclosed
US-20060074165-A1 Laser light absorbing additive MERCK PATENT GMBH (DE) 2006-04-06 US disclosed
US-20050222328-A1 Polymer composition with improved temperature resistance DSM IP ASSETS B.V. (NL) 2005-10-06 US disclosed
EP-1567594-A1 LASER LIGHT ABSORBING ADDITIVE DSM IP Assets B.V. (NL) 2005-08-31 EP disclosed
EP-1567595-A1 LASER WRITABLE COMPOSITION DSM IP Assets B.V. (NL) 2005-08-31 EP disclosed
EP-1492843-A1 POLYMER COMPOSITION WITH IMPROVED TEMPERATURE RESISTANCE DSM IP Assets B.V. (NL) 2005-01-05 EP disclosed
WO-2004096916-A1 COMPOSITION WHICH CONTAINS BITUMEN AND POLYETHYLENE DSM IP ASSETS B.V. (NL) 2004-11-11 WO disclosed
WO-2004050766-A1 LASER LIGHT ABSORBING ADDITIVE DSM IP ASSETS B.V. (NL) 2004-06-17 WO disclosed
WO-2004050767-A1 LASER WRITABLE COMPOSITION DSM IP ASSETS B.V. (NL) 2004-06-17 WO disclosed
WO-2003087216-A1 POLYMER COMPOSITION WITH IMPROVED TEMPERATURE RESISTANCE DSM IP ASSETS B.V. (NL) 2003-10-23 WO disclosed