Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.56 |
| ▸ | HTR7 | P34969 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | HRH1 | P35367 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 4/20 | 0.51 |
| ▸ | DRD3 | P35462 | 4/20 | 0.51 |
| ▸ | HTR2A | P28223 | 4/20 | 0.50 |
| ▸ | HTR2C | P28335 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11454884 | 0.94 | HTR1A (0.59) | HTR1AHTR7HSD17B10KCNH2HRH1 | |
| SCHEMBL11465556 | 0.89 | HTR1A (0.58) | HTR1AHTR7DRD2HTR2AMEN1 | |
| SCHEMBL11456938 | 0.88 | HTR1A (0.71) | HTR1AHTR7KCNH2DRD2HTR2A | |
| SCHEMBL11456939 | 0.88 | HTR1A (0.59) | HTR1AHTR7DRD2DRD3HTR2A | |
| Methane SCHEMBL11605143 | 0.88 | HTR1A (0.57) | HTR1AHTR7DRD2HTR2AMEN1 | |
| SCHEMBL11465074 | 0.88 | HTR1A (0.52) | HTR1AHTR7DRD2DRD3MEN1 | |
| SCHEMBL11448262 | 0.87 | HTR1A (0.58) | HTR1AHTR7DRD2DRD3MEN1 | |
| SCHEMBL11446702 | 0.87 | HTR1A (0.67) | HTR1AHTR7KCNH2DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL11500448 | 0.86 | HTR1A (0.57) | HTR1AHTR7HSD17B10DRD2DRD3 | |
| SCHEMBL11446419 | 0.86 | HSD17B10 (0.54) | HTR1AHTR7HSD17B10KCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4205173-A | 1-Heterocyclic alkyl-1,2,3,4-tetrahydroquinazolinones and analgesic intermediates thereof | PENNWALT CORPORATION (US) | 1980-05-27 | — | — | US | disclosed |
| US-4085107-A | ANALGESICS | PENNWALT CORPORATION (US) | 1978-04-18 | — | — | US | disclosed |