Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7458656 | 0.73 | OPRK1 (0.37) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7458637 | 0.68 | RPS6KA3 (0.37) | HPGDSMN1; SMN2HSD17B3 | |
| SCHEMBL7457955 | 0.68 | MAPT (0.39) | HPGDSMN1; SMN2HSD17B3 | |
| SCHEMBL28294007 | 0.67 | MAPT (0.34) | HPGDSMN1; SMN2 | |
| SCHEMBL9635032 | 0.62 | HTT (0.42) | NPC1RAB9A | |
| SCHEMBL11448289 | 0.61 | CCNB2 (0.37) | HSD17B3 | |
| SCHEMBL11448549 | 0.61 | AURKA (0.39) | HSD17B3 | |
| SCHEMBL8526930 | 0.58 | HTR5A (0.40) | HSD17B3 | |
| SCHEMBL9512603 | 0.57 | HPGD (0.34) | HPGD | |
| SCHEMBL5594805 | 0.57 | CYP1A2 (0.43) | HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4223136-A | 2,3-Dihydro-3-oxo-5H-pyrido[3,4-b][1,4]-benzothiazine-4-carbonitriles | G. D. SEARLE & CO. (US) | 1980-09-16 | — | — | US | disclosed |