Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.31 |
| ▸ | CDC25A | P30304 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | STK10 | O94804 | 1/20 | 0.30 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9185130 | 0.75 | MAPT (0.34) | MAPTACHEHPGDALDH1A1KDM4E | |
| SCHEMBL11406516 | 0.73 | CCNB2 (0.45) | MAPTHPGDSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL28294000 | 0.73 | ACHE (0.33) | MAPTACHEALDH1A1KDM4EMEN1 | |
| SCHEMBL18485263 | 0.70 | TDP2 (0.35) | MAPTSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL11447993 | 0.67 | HPGD (0.33) | HPGDSMN1; SMN2 | |
| SCHEMBL7764516 | 0.64 | MAOA (0.44) | ACHEALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL25112085 | 0.63 | ACHE (0.41) | ACHEHPGDSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL2821364 | 0.63 | MAPT (0.52) | MAPTHPGDALDH1A1KDM4EKMT2A | |
| SCHEMBL9177075 | 0.61 | KMT2A (0.41) | MAPTACHEHPGDALDH1A1KDM4E | |
| SCHEMBL3853426 | 0.59 | AHR (0.39) | MAPTACHEHPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715159-A | Anticancer medicine composition | 国立癌症中心 | 2019-05-03 | — | — | CN | claimed |
| CN-109715607-A | Compounds that inhibit the formation of the C-MYC/MAX/DNA complex | 国立癌症中心 | 2019-05-03 | — | — | CN | claimed |