Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 13/20 | 0.49 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11448956 | 0.96 | PTPRZ1 (0.46) | LTA4HPTPRZ1CHEK2 | |
| SCHEMBL11448940 | 0.85 | CHRNB4 (0.43) | LTA4HCHEK2 | |
| SCHEMBL11447921 | 0.83 | LTA4H (0.47) | LTA4HCHEK2 | |
| SCHEMBL7116280 | 0.83 | LTA4H (0.70) | LTA4HCHEK2 | |
| Hydrochloric Acid SCHEMBL4321733 | 0.82 | LTA4H (0.51) | LTA4HCHEK2NFE2L2 | |
| SCHEMBL11448286 | 0.81 | CHRNB4 (0.46) | — | |
| SCHEMBL6608869 | 0.81 | LTA4H (0.68) | LTA4HCHEK2 | |
| SCHEMBL11455868 | 0.79 | LTA4H (0.64) | LTA4H | |
| SCHEMBL11447738 | 0.79 | LTA4H (0.45) | LTA4HCHEK2 | |
| SCHEMBL2185418 | 0.78 | LTA4H (0.50) | LTA4HCHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4225608-A | ANTIDEPRESSANTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-09-30 | — | — | US | disclosed |