Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALPL | P05186 | 2/20 | 0.41 |
| ▸ | ALPI | P09923 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11622460 | 0.93 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL11450010 | 0.86 | ALPL (0.56) | ALDH1A1SMN1; SMN2ALPLALPIHPGD | |
| SCHEMBL11448192 | 0.85 | GAA (0.42) | ALDH1A1MEN1KMT2APKMSMN1; SMN2 | |
| SCHEMBL11448951 | 0.84 | MAPT (0.52) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL11448846 | 0.84 | MAPT (0.59) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL11448906 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL11460035 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL10892487 | 0.82 | TSHR (0.58) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL11841583 | 0.80 | GAA (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11448389 | 0.80 | SMN1; SMN2 (0.60) | ALDH1A1MEN1KMT2APOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216161-A | 3,4-Diaminophenyl sulfonic acid esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-08-05 | — | — | US | disclosed |
| US-4069325-A | 3-Carbalkoxyamino-1H-2,1,4-benzothiadiazine derivatives | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-01-17 | — | — | US | disclosed |
| US-3996369-A | Anthelmintically active 2-carbalkoxyamino benzimidazolyl-5(6)-sulfonic acid phenyl esters | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-12-07 | — | — | US | disclosed |