Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11448192 | 0.92 | GAA (0.42) | GAAMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL11622460 | 0.85 | ALDH1A1 (0.44) | GAAMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL11848703 | 0.82 | CA1 (0.56) | GAAMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL11844829 | 0.82 | CA12 (0.56) | GAAMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL11081800 | 0.81 | TDP1 (0.47) | GAAMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL11844196 | 0.81 | FFAR4 (0.43) | GAAMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL11448446 | 0.80 | ALDH1A1 (0.47) | GAATDP1L3MBTL1LMNAHTT | |
| SCHEMBL11852879 | 0.79 | MEN1 (0.56) | TDP1L3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL11844234 | 0.79 | TDP1 (0.62) | GAAMAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL11082558 | 0.78 | L3MBTL1 (0.47) | GAAMAPK1TDP1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3996368-A | Anthelmintically active 2-carbalkoxyamino-5(6)-phenyl sulfonyloxy benzimidazoles | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-12-07 | — | — | US | disclosed |