Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MASP2 | O00187 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | MLKL | Q8NB16 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11403949 | 0.98 | ALDH1A1 (0.51) | ALDH1A1POLBIDO1TAAR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5845865 | 0.82 | TAAR1 (0.65) | ALDH1A1POLBIDO1TAAR1L3MBTL1 | |
| SCHEMBL11307180 | 0.81 | ALDH1A1 (0.58) | ALDH1A1POLBIDO1TAAR1L3MBTL1 | |
| SCHEMBL2944008 | 0.81 | RAB9A (0.54) | ALDH1A1POLBIDO1TAAR1L3MBTL1 | |
| SCHEMBL9314968 | 0.77 | IDO1 (0.53) | ALDH1A1POLBIDO1TAAR1L3MBTL1 | |
| SCHEMBL3225709 | 0.76 | TAAR1 (0.61) | ALDH1A1POLBIDO1TAAR1L3MBTL1 | |
| SCHEMBL9255168 | 0.76 | ALDH1A1 (0.59) | ALDH1A1POLBIDO1TAAR1L3MBTL1 | |
| SCHEMBL14029834 | 0.75 | TAAR1 (0.56) | ALDH1A1POLBIDO1TAAR1L3MBTL1 | |
| SCHEMBL3221142 | 0.75 | TAAR1 (0.60) | ALDH1A1POLBIDO1TAAR1L3MBTL1 | |
| SCHEMBL3523940 | 0.75 | TAAR1 (0.69) | ALDH1A1POLBIDO1TAAR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228291-A | INHIBITORS OF HISTAMINE ACTIVITY | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-10-14 | — | — | US | disclosed |