Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MASP2 | O00187 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | MLKL | Q8NB16 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3221142 | 0.95 | TAAR1 (0.60) | TAAR1ALDH1A1POLBIDO1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5400129 | 0.94 | TAAR1 (0.58) | TAAR1ALDH1A1POLBIDO1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5845865 | 0.90 | TAAR1 (0.65) | TAAR1ALDH1A1POLBIDO1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL5411341 | 0.87 | TAAR1 (0.49) | TAAR1ALDH1A1POLBIDO1KMT2A | |
| SCHEMBL3523940 | 0.83 | TAAR1 (0.69) | TAAR1ALDH1A1POLBIDO1L3MBTL1 | |
| SCHEMBL14029834 | 0.83 | TAAR1 (0.56) | TAAR1ALDH1A1POLBIDO1L3MBTL1 | |
| SCHEMBL27735848 | 0.83 | TAAR1 (0.68) | TAAR1ALDH1A1POLBIDO1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5846488 | 0.82 | TAAR1 (0.67) | TAAR1ALDH1A1POLBIDO1L3MBTL1 | |
| SCHEMBL14005055 | 0.81 | TAAR1 (0.54) | TAAR1ALDH1A1POLBIDO1L3MBTL1 | |
| SCHEMBL27980611 | 0.79 | TAAR1 (0.67) | TAAR1ALDH1A1POLBIDO1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190040073-A1 | NONANOIC AND DECANOIC ACID DERIVATIVES AND USES THEREOF | SCIFLUOR LIFE SCIENCES, INC. | 2019-02-07 | — | — | US | disclosed |
| US-10118929-B2 | Nonanoic and decanoic acid derivatives and uses thereof | SCIFLUOR LIFE SCIENCES, INC. (US) | 2018-11-06 | — | — | US | disclosed |
| US-20170313708-A1 | NONANOIC AND DECANOIC ACID DERIVATIVES AND USES THEREOF | FELIQS CORPORATION (JP) | 2017-11-02 | — | — | US | disclosed |
| US-20100048536-A1 | Novel Substituted Diaryl Azepine Derivatives as Integrin Ligands | GENESTE HERVE | 2010-02-25 | — | — | US | disclosed |
| US-20080221082-A1 | Ligands of Integrin Receptors | ABBOTT GMBH & CO. KG (DE) | 2008-09-11 | — | — | US | disclosed |
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |
| EP-1286673-B8 | LIGANDS OF INTEGRIN RECEPTORS | ABBOTT GMBH & CO KG (DE) | 2005-07-20 | — | — | EP | disclosed |
| EP-1286673-B1 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2005-05-25 | — | — | EP | disclosed |
| US-20040077638-A1 | Novel integrin receptor antagonists | BASF AKTIENGESELLCHAFT (DE) | 2004-04-22 | — | — | US | disclosed |
| US-20040063934-A1 | Integrin ligands | ABBVIE DEUTSCHLAND GMBH & CO KG (DE) | 2004-04-01 | — | — | US | disclosed |
| EP-1307443-A2 | NOVEL SUBSTITUTED DIARYL AZEPINE DERIVATIVES AS INTEGRIN LIGANDS | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-07 | — | — | EP | disclosed |
| EP-1289962-A1 | INTEGRIN LIGANDS | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-12 | — | — | EP | disclosed |
| EP-1286673-A2 | LIGANDS OF INTEGRIN RECEPTORS | Basf Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2002051810-A2 | INTEGRIN RECEPTOR LIGANDS | ABBOTT GMBH & CO. KG (DE) | 2002-07-04 | — | — | WO | disclosed |
| WO-2002014320-A2 | NOVEL SUBSTITUTED DIARYL AZEPINE DERIVATIVES AS INTEGRIN LIGANDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-21 | — | — | WO | disclosed |
| WO-2001096312-A1 | INTEGRIN LIGANDS | BASF AKTIENGESELLSCHAFT (DE) | 2001-12-20 | — | — | WO | disclosed |
| WO-2001093840-A2 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2001-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048536-A1 | Novel Substituted Diaryl Azepine Derivatives as Integrin Ligands | ITGB3, ITGAL, ITGB4 | TAAR1 1085/4885ALDH1A1 1678/4885POLB 4840/4885 |
| US-20040063934-A1 | Integrin ligands | ITGB3, ITGAV, ITGAL | TAAR1 2773/4885ALDH1A1 2630/4885POLB 4577/4885 |
| US-20040077638-A1 | Novel integrin receptor antagonists | ITGB3, ITGAV, ITGA2B | TAAR1 2079/4885ALDH1A1 3214/4885POLB 4717/4885 |
| US-20190040073-A1 | NONANOIC AND DECANOIC ACID DERIVATIVES AND USES THEREOF | FFAR3, FFAR2, FFAR1 | TAAR1 2878/4885ALDH1A1 1356/4885POLB 4074/4885 |
| US-20080221082-A1 | Ligands of Integrin Receptors | ITGB3, ITGAV, ITGA2B | TAAR1 2007/4885ALDH1A1 2222/4885POLB 4398/4885 |
| US-10118929-B2 | Nonanoic and decanoic acid derivatives and uses thereof | FFAR3, FFAR2, FFAR1 | TAAR1 2878/4885ALDH1A1 1356/4885POLB 4074/4885 |
| US-20170313708-A1 | NONANOIC AND DECANOIC ACID DERIVATIVES AND USES THEREOF | FFAR3, FFAR2, FFAR1 | TAAR1 2878/4885ALDH1A1 1356/4885POLB 4074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.